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Advances in management of pediatric chronic immune thrombocytopenia: a narrative review

Jae Min Lee1

  • 1Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.

Journal of Yeungnam Medical Science
|January 9, 2023
PubMed

Immune thrombocytopenia (ITP) is a disease in which thrombocytopenia occurs because of immune-mediated platelet destruction and decreased platelet production. Although many pediatric patients with ITP experience spontaneous remission or reach remission within 12 months of first-line therapy, approximately 20% progress to chronic ITP. Patients who do not respond to first-line treatment or experience frequent relapses are of great concern to physicians. This review summarizes recent treatments for second-line treatment of pediatric chronic ITP.

Keywords:
DapsoneIdiopathic thrombocytopenic purpuraRituximabSplenectomyThrombopoietin

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