Related Experiment Video
Updated: Aug 14, 2025

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Right-deviating prismatic adaptation reduces obsessions in a community sample
Barbara Magnani1, Francesca Frassinetti2,3, Christian Franceschini4
1Department of Humanities, Social Sciences and Cultural Industries, University of Parma, Parma, Italy.
Background And Aims:
Patients with obsessive-compulsive (OC) disorder are impaired in disengaging attention from negative valence stimuli and show an attentional bias toward the right space. This pattern in OC disorder is similar to the impaired disengagement of attention from stimuli in the ipsilesional space as a consequence of a right-hemispheric cerebral lesion in patients with neglect, suggesting a right hemispheric dysfunction in patients with OC disorder. The attentional impairment in patients with neglect is reduced by a visuomotor procedure, such as prismatic adaptation (PA) with right-deviating lenses. Thus, here, we explored whether right-deviating PA is also effective in reducing OC psychological symptoms.
Methods:
Participants with a high rate of OC symptoms completed self-report measures of such symptoms before and after right- or left-deviating PA.
Results:
Right-deviating PA, and not left-deviating PA, reduced OC symptoms more prominently on obsessions than compulsions.
Conclusion:
Results support the idea that right-deviating PA might be considered an effective technique to modulate OC symptoms. This has implications for theories about the underlying mechanisms of OC symptoms and the consideration of PA as a complementary procedure to psychological treatments.
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