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Juvenile polyposis syndrome: A case report

Edwin Mogere1, Elijah Mwaura2, Mark Waithaka2

  • 1Murang'a Level 5 Hospital Murang'a Kenya.

Clinical Case Reports
|January 9, 2023
PubMed

Insights

Juvenile polyposis syndrome (JPS) is a genetic disorder causing numerous hamartomatous polyps. Individuals with JPS face a higher risk of colorectal and gastric cancers, necessitating surgical intervention.

Area of Science:

  • Gastroenterology
  • Genetics
  • Oncology

Background:

  • Juvenile polyposis syndrome (JPS) is an autosomal dominant inherited condition.
  • It is characterized by the development of multiple hamartomatous polyps in the gastrointestinal tract.

Observation:

  • Patients diagnosed with JPS exhibit an elevated risk for developing colorectal and gastric cancers.
  • Diagnosis is typically confirmed through endoscopic visualization and histological examination of polyps.

Findings:

  • The study details a case of JPS managed with surgical intervention.
  • The surgical procedure included a total proctocolectomy with an ileal pouch-anal anastomosis.

Implications:

  • Early diagnosis and management of JPS are crucial for cancer risk reduction.
  • Surgical options like proctocolectomy and ileal pouch-anal anastomosis can be effective in managing severe JPS cases.
  • Further research into genetic counseling and long-term surveillance for JPS patients is warranted.

Keywords:
colon cancergastroenterologyjuvenile polyposis syndrome

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