Related Experiment Video

Updated: Aug 14, 2025

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

7.2K

Concurrent Collagenous Gastritis and Collagenous Colitis: A Case Presentation and Review of the Literature

Hossein Ziaei1, Amirhossein Boghratian1,2, Masoudreza Sohrabi1

  • 1Gastrointestinal and liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.

Middle East Journal of Digestive Diseases
|January 9, 2023
PubMed

Insights

Simultaneous collagenous gastritis and collagenous colitis, a rare gastrointestinal disorder, were observed in a 31-year-old male. This case highlights an unusual co-occurrence of these distinct collagenous conditions.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Collagenous gastritis is a rare condition characterized by a thickened subepithelial collagen layer in the stomach.
  • Collagenous colitis is a distinct condition affecting the colon, also marked by subepithelial collagen deposition.

Observation:

  • A 31-year-old male presented with symptoms including dyspepsia, anemia, and weight loss.
  • Endoscopic examination revealed irregular gastric atrophy but a normal colon.

Findings:

  • Gastric biopsies confirmed the presence of collagenous gastritis, showing increased thickness and a subepithelial collagen band.
  • The patient exhibited simultaneous collagenous gastritis and collagenous colitis, an exceptionally rare presentation.

Implications:

  • This case underscores the possibility of co-occurring collagenous conditions in the upper and lower gastrointestinal tracts.
  • Further research may elucidate sharedPathogenic mechanisms or risk factors for simultaneous collagenous gastritis and colitis.

Keywords:
Collagenous colitisCollagenous gastritisColonStomach

More Related Videos

Modeling Colitis-Associated Cancer with Azoxymethane AOM and Dextran Sulfate Sodium DSS12:37

Modeling Colitis-Associated Cancer with Azoxymethane AOM and Dextran Sulfate Sodium DSS

Published on: September 11, 2012

47.1K
Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

427

Related Concept Videos

Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
437
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
380
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
682
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
276
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
334
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
250