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Follow-up study of depressive state on patients with atrial fibrillation 1 year after radio-frequency ablation

Lei Ren1, Wenjun Li1, Xin Su1

  • 1Department of Cardiovascular Medicine, Fuyang People's Hospital Affiliated to Anhui Medical University, Fuyang, China.

Frontiers in Psychiatry
|January 9, 2023
PubMed

Insights

Depression significantly increases the risk of atrial fibrillation (AF) recurrence after radio-frequency ablation. Even mild depression elevates recurrence risk by 74%, highlighting the importance of addressing mental health in AF management.

Area of Science:

  • Cardiology
  • Psychiatry

Background:

  • Atrial fibrillation (AF) is a common arrhythmia often treated with radio-frequency ablation.
  • Depression is prevalent in AF patients and may impact treatment outcomes.

Purpose of the Study:

  • To investigate the association between depression and AF recurrence 1 year post-radio-frequency ablation.

Main Methods:

  • 91 AF patients undergoing radio-frequency ablation were assessed for depression using the Self-rating Depression Scale (SDS).
  • Patients were categorized into recurrence and no-recurrence groups 1 year post-ablation.
  • Logistic regression analysis identified factors influencing AF recurrence.

Main Results:

  • Higher age, longer disease duration, increased BMI, and larger left atrial diameter were observed in the recurrence group.
  • Elevated neutrophil and monocyte counts, and lower lymphocyte counts were noted in patients with recurrence.
  • Moderate to major depression significantly correlated with higher AF recurrence rates, with increased risk percentages for mild, moderate, and major depression.

Conclusions:

  • Depression is a significant independent factor associated with AF recurrence after radio-frequency ablation.
  • Addressing depression in AF patients is crucial for improving long-term outcomes post-ablation.
Abstract

Keywords:
AFSDSdepressionradio frequency ablationrecurrence

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