A Descriptive Study of Atherogenic Indices in Patients Admitted to a Tertiary Care Hospital

Saranya Dharmaraj1, Sujatha Rajaragupathy2, Saju Denishya2

  • 1Biochemistry, Employees' State Insurance Corporation (ESIC) Medical College, Hyderabad, IND.

Cureus
|January 9, 2023
PubMed

Insights

Atherogenic indices, like non-high-density lipoprotein cholesterol, may indicate coronary artery disease and statin use in hospitalized patients. However, these indices do not reliably predict hospital stay duration.

Area of Science:

  • Cardiology
  • Clinical Biochemistry
  • Public Health

Background:

  • Atherogenic indices are valuable, non-invasive tools for assessing dyslipidemias and cardiometabolic risk.
  • Evaluating these indices in hospitalized patients can aid in prognosis and management.

Purpose of the Study:

  • To assess atherogenic index profiles in hospitalized patients.
  • To correlate these indices with comorbidities, statin use, and hospital stay duration.

Main Methods:

  • Cross-sectional study of 412 hospitalized adults (>18 years).
  • Calculation of atherogenic indices from lipid profiles.
  • Statistical analysis using Mann-Whitney U and Spearman's rank correlation tests.

Main Results:

  • Non-high-density lipoprotein cholesterol showed significant association with coronary artery disease (p=0.0112) and statin use (p=0.0057).
  • No significant differences in other atherogenic indices across comorbidities or statin use.
  • Atherogenic indices did not correlate with hospital stay duration (p>0.05).

Conclusions:

  • Non-high-density lipoprotein cholesterol may serve as a potential biomarker for coronary artery disease and statin use.
  • Other traditional atherogenic indices are not reliable predictors of hospital stay duration in this cohort.

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