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Unicentric Castleman's Disease Presenting As Back Pain.
Nadezda Buntic1, Taylor Brown2, Ummah Salma Nisar3
1Medicine, Lincoln Memorial University-DeBusk College of Osteopathic Medicine, Harrogate, USA.
Cureus
|January 9, 2023
Summary
Castleman's disease is a rare B-cell lymphoproliferative disorder. This case report highlights a rare extrathoracic mass presentation causing back pain in an elderly male patient.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Castleman's disease is a rare lymphoproliferative disorder involving B lymphocytes and plasma cells.
- Multicentric Castleman's disease is frequently associated with HIV or Kaposi's Sarcoma.
- Unicentric Castleman's disease typically presents as a thoracic lymph node enlargement but can occur elsewhere.
Observation:
- A case report of a 71-year-old man with a rare large extrathoracic mass is presented.
- The mass caused significant back pain, indicating an unusual presentation.
Findings:
- The case illustrates a rare extrathoracic manifestation of Castleman's disease.
- This presentation differs from the typical thoracic lymph node involvement.
Implications:
- Highlights the importance of considering Castleman's disease in the differential diagnosis of extrathoracic masses, even with atypical symptoms like back pain.
- Emphasizes the diverse clinical presentations of Castleman's disease, necessitating broad diagnostic considerations.
- Contributes to the understanding of rare Castleman's disease variants and their management.
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