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Updated: Aug 14, 2025
06:29
Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation
Published on: May 2, 2020
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Features and influences on the normal tear evaporation rate
Naeimeh Monfared1, Paul J Murphy1
1School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.
Summary
Understanding normal tear evaporation rates (TER) is key for diagnosing evaporative dry eye disease. This review explores ocular, environmental, and systemic factors influencing TER, essential for accurate diagnosis and management.
Area of Science:
- Ophthalmology
- Physiology
Background:
- Tear evaporation is a normal physiological process crucial for ocular surface homeostasis.
- An abnormal tear evaporation rate (TER) is a hallmark of evaporative dry eye disease (DED).
- Measuring TER is a valuable diagnostic tool for DED.
Purpose of the Study:
- To review and synthesize current knowledge on factors influencing normal tear evaporation rates (TER).
- To elucidate the range of normal TER and identify key influencing factors for improved DED diagnosis.
Main Methods:
- Literature review of scientific publications.
- Analysis of studies reporting normal TER values and influencing factors.
Main Results:
- Normal TER values exhibit significant variability.
- Ocular, environmental, and systemic factors demonstrably impact TER.
- Specific factors contributing to TER variation are detailed.
Conclusions:
- A comprehensive understanding of factors affecting normal TER is crucial for accurate DED diagnosis.
- Further research into TER determinants can refine diagnostic criteria and management strategies for dry eye disease.
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