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The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods.

Matthew C Mauck1, Jeffrey Lotz2, Matthew A Psioda1

  • 1University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Pain Medicine (Malden, Mass.)
|January 9, 2023
PubMed
Summary

Chronic low back pain (cLBP) affects many adults, leading to over-reliance on opioids. The NIH Back Pain Consortium (BACPAC) Research Program aims to improve cLBP diagnosis and treatment, addressing the opioid crisis.

Keywords:
BACPAC Research ConsortiumBack PainChronic low back pain (cLBP)HEALHarmonizationSMARTchronic diseasechronic painclinical trialslow back pain

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Area of Science:

  • Pain Management
  • Public Health
  • Clinical Research

Background:

  • Back pain is a prevalent issue affecting a significant portion of the adult population.
  • Chronic low back pain (cLBP) presents complex challenges in diagnosis and treatment, often involving biological, psychological, and social factors.
  • Over-reliance on opioid medications for cLBP contributes to the opioid use disorder epidemic and associated mortality.

Purpose of the Study:

  • To provide an overview of the NIH Back Pain Consortium (BACPAC) Research Program's structure and goals.
  • To describe harmonization efforts and the research agenda within the BACPAC network.
  • To serve as a blueprint for future pain research consortia.

Main Methods:

  • The BACPAC Research Program is a network of 14 funded entities established under the NIH HEAL initiative.
  • Harmonization efforts focus on standardizing data and methodologies across consortium members.
  • A collaborative project is being developed to leverage the network's collective strengths.

Main Results:

  • The BACPAC program aims to address limitations in the diagnosis and treatment of cLBP.
  • The initiative seeks to foster collaboration and resource sharing among diverse research groups.
  • Standardized approaches are being implemented to enhance research efficiency and comparability.

Conclusions:

  • The BACPAC Research Program is a structured initiative to advance scientific understanding and treatment of chronic low back pain.
  • This consortium model facilitates collaborative research and aims to mitigate the impact of the opioid crisis.
  • The program's framework offers a model for future large-scale, multi-entity research endeavors in pain science.