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Respiratory Epithelial Adenomatoid Hamartoma.
Ashley F Schemel1, Katherine M Zamperini2, Karl A Soderlund3
1Department of Otolaryngology, Naval Medical Readiness and Training Command - Portsmouth, 620 John Paul Jones Cir, Portsmouth, VA, 23708, USA. halbertaf@gmail.com.
Head and Neck Pathology
|January 9, 2023
Summary
Respiratory Epithelial Adenomatoid Hamartoma (REAH) is a rare sinonasal tumor. Accurate diagnosis through clinical, radiologic, and histologic evaluation is key to appropriate patient management and avoiding unnecessary treatments.
Area of Science:
- Otorhinolaryngology
- Pathology
- Radiology
Background:
- Respiratory Epithelial Adenomatoid Hamartoma (REAH) is an uncommon benign sinonasal tumor.
- Misdiagnosis as malignancy can lead to patient morbidity.
- Accurate clinical and histological diagnosis is critical.
Observation:
- Patient presented with a bilateral olfactory cleft mass.
- CT revealed a non-enhancing homogenous mass in the olfactory cleft.
- MRI showed a homogenous cribriform mass with defined borders and characteristic signal intensities.
Findings:
- Histological examination showed glands lined with ciliated respiratory epithelium and stroma.
- Surface epithelium communicated with proliferating submucosal glands.
- The findings were consistent with a classic presentation of REAH.
Implications:
- This case highlights the importance of accurate diagnosis of REAH.
- Understanding REAH allows for appropriate patient counseling.
- Management options range from observation to surgical intervention.
