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Tunneling-to-Hopping Transition in Multiheme Cytochrome Bioelectronic Junctions.

Zdenek Futera1, Xiaojing Wu2, Jochen Blumberger2

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Multiheme cytochromes exhibit long-range coherent tunneling due to their unique electronic properties. This allows for efficient electron transport in nanobioelectronic junctions, challenging previous transport models.

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Area of Science:

  • Biophysics
  • Nanotechnology
  • Materials Science

Background:

  • Multiheme cytochromes (MHCs) are proteins of interest for nanobioelectronic junctions due to their high electronic conductance.
  • Recent studies on dry MHC junctions indicated coherent tunneling over unexpectedly long distances (>3 nm).

Purpose of the Study:

  • To investigate the mechanism behind long-distance coherent transport in MHCs.
  • To understand the factors governing electron transport in MHC-based nanobioelectronic junctions.

Main Methods:

  • Theoretical analysis of electron transport mechanisms in MHCs.
  • Modeling of coherent tunneling and incoherent hopping transport.
  • Investigation of the role of protein electronic states and interface energy levels.

Main Results:

  • A low exponential distance decay constant (β = 0.2 Å⁻¹) for coherent conduction in MHCs was identified.
  • A high density of protein electronic states prolongs the coherent tunneling regime beyond that of small molecule wires.
  • Incoherent hopping is suppressed by a significant energy level offset at the protein-electrode interface.

Conclusions:

  • MHCs facilitate long-range coherent electron transport due to their intrinsic electronic structure.
  • Modulating the interface energy offset can shift the transport mechanism from coherent tunneling to incoherent hopping.
  • This understanding enables potential for micrometer-scale transport in MHC-based devices.