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Unilateral lupus mastitis.
Alicia Jiménez-Antón1, David Jiménez-Gallo1, José Francisco Millán-Cayetano1
1Unidad de Gestión Clínica de Dermatología Médico-Quirúrgica y Venereología, 16824Hospital Universitario Puerta del Mar, Cádiz, Spain.
Lupus
|January 9, 2023
Summary
Lupus mastitis, a rare condition linked to lupus erythematosus, requires accurate diagnosis to distinguish it from breast cancer. Hydroxychloroquine effectively treats this condition, as demonstrated in a recent case study.
Area of Science:
- Dermatology
- Rheumatology
- Oncology
Background:
- Lupus mastitis is an uncommon manifestation of systemic lupus erythematosus (SLE) or discoid lupus erythematosus (DLE).
- Accurate differentiation from inflammatory breast cancer is crucial for appropriate patient management.
- Histopathological examination reveals adipose tissue involvement consistent with cutaneous lupus erythematosus.
Observation:
- A case of unilateral lupus mastitis in a patient without a prior lupus diagnosis was observed.
- Histological findings confirmed lupus mastitis with characteristic features of cutaneous lupus erythematosus.
- Direct immunofluorescence identified the lupus band at the dermal-epidermal junction.
Findings:
- The patient presented with unilateral lupus mastitis.
- Complete remission was achieved using hydroxychloroquine and topical corticosteroids.
- This highlights the efficacy of hydroxychloroquine as a primary treatment modality.
Implications:
- Early and accurate diagnosis of lupus mastitis is essential to avoid misdiagnosis with breast cancer.
- Hydroxychloroquine is the recommended treatment for lupus mastitis.
- This case underscores the importance of considering lupus erythematosus in patients presenting with inflammatory breast conditions.
