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A simplified thin-layer chromatography system for the detection of commonly abused basic drugs
1Department of Analytical Pharmacology, Ealing Hospital, Southall, Middlesex, UK.
Annals of Clinical Biochemistry
|September 1, 1987
Abstract:
A simple method for the detection of drugs of abuse and their metabolites in urine is described. By extraction of urine (20 mL) with a buffered ToxElut solid phase column all the commonly abused opioid drugs can be detected on a single thin-layer chromatography plate. Location of the spots is achieved by spraying the plate with iodoplatinate following acidification with dilute sulphuric acid. Sensitivity of the order of 1 mg/L is attained for most drugs.