The 2023 Nucleic Acids Research Database Issue and the online molecular biology database collection

Area of Science:

• Bioinformatics
• Computational Biology
• Genomics
• Immunoinformatics
• Structural Biology

Background:

• The Nucleic Acids Research (NAR) Database Issue is a key annual publication.
• It serves as a vital resource cataloging biological databases for the scientific community.
• Keeping this catalog current is essential for researchers accessing biological data.

Purpose of the Study:

• To present the 2023 Nucleic Acids Research Database Issue.
• To highlight new and updated biological databases across various research domains.
• To provide an updated catalog of molecular biology databases.

Main Methods:

• Compilation of submitted database articles.
• Review and categorization of new and updated database resources.
• Inclusion of Breakthrough Articles for significant database advancements.

Main Results:

• The 2023 Issue includes 178 papers: 90 new databases and 82 updates.
• Key updates include Genbank, ENA, ChIPBase, JASPAR, mirDIP, NACDDB, BMRB, RCSB, AlphaFold 2, STRING, REBASE, CEDAR, IPD-IMGT/HLA, PGG.MHC, Ensembl, GWAS Central, UCSC Genome Browser, Open Targets, DrugCentral, CTD, and Pubchem.
• The NAR online Molecular Biology Database Collection now totals 1764 databases, with 92 new entries and 463 revisited.

Conclusions:

• The 2023 NAR Database Issue provides a comprehensive and up-to-date overview of biological databases.
• It facilitates access to critical data for research in genomics, proteomics, immunology, and drug discovery.
• The continuous update of the NAR database collection ensures researchers have access to the latest bioinformatics tools and resources.