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Decrease in Gait Speed Over Time Is Associated With Increase in Number of Depression Symptoms in Older Adults With
Inbar Lavie1, Michal Schnaider Beeri2,3,4, Yonathan Schwartz2
1Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Summary
In older adults with type 2 diabetes, slower gait speed and decreased grip strength are linked to depression. Gait speed decline may predict future depression, aiding prevention strategies.
Area of Science:
- Geriatric Medicine
- Neurology
- Endocrinology
Background:
- Investigates motor function and depression in older adults with type 2 diabetes (T2D).
- Utilizes data from the longitudinal Israel Diabetes and Cognitive Decline (IDCD) study (n=984).
- Examines cross-sectional and longitudinal relationships.
Purpose of the Study:
- To explore the associations between motor functions (grip strength, gait speed) and depression symptoms.
- To identify potential predictors of depression in individuals with T2D.
- To inform the development of depression prevention strategies.
Main Methods:
- Hierarchical Linear Mixed Models (HLMM) were employed.
- Adjusted for sociodemographic, cardiovascular, cognitive, and exhaustion factors.
- Evaluated grip strength, gait speed, and Geriatric Depression Scale (GDS) scores over time.
Main Results:
- Slower baseline gait speed correlated with higher GDS scores and increased depression over time.
- Decreased gait speed predicted increased GDS scores.
- Lower baseline grip strength associated with higher GDS scores, but not depression trajectories.
- Faster grip strength decline linked to faster GDS score increases.
Conclusions:
- Both gait speed and grip strength show cross-sectional links to depression.
- Gait speed, particularly its decline, may predict incident depression symptoms.
- Findings support gait speed assessment for depression risk stratification and prevention in T2D.
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