Related Experiment Video
Updated: Aug 14, 2025
Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
Published on: June 5, 2019
Heart rate variability as an indicator of COVID-19 induced myocardial injury: a retrospective cohort study
Hani Taman1, Nabil Mageed1, Mohamed Elmorsy2
1Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University, 2 El-Gomhouria Street, Mansoura, 35516, Egypt.
Insights
Heart rate variability (HRV) indices were significantly lower in COVID-19 patients with myocardial injury. This suggests HRV can help identify cardiac issues in severe COVID-19 cases.
Area of Science:
- Cardiology
- Autonomic Nervous System Research
- Infectious Disease Epidemiology
Background:
- Heart rate variability (HRV) reflects autonomic nervous system function.
- HRV may serve as a prognostic indicator for myocardial injury in COVID-19 patients.
- COVID-19 can affect cardiac health, necessitating methods to assess myocardial injury.
Purpose of the Study:
- To compare HRV indices between COVID-19 patients with and without myocardial injury.
- To investigate the utility of HRV in identifying cardiac complications in ICU COVID-19 patients.
Main Methods:
- Retrospective analysis of 238 adult COVID-19 patients admitted to the ICU.
- Collected daily R-R intervals, SDANN, and RMSSD data for the first five ICU days.
- Patients were categorized into myocardial injury and non-myocardial injury groups.
Main Results:
- Significantly shorter R-R intervals, SDANN, and RMSSD were observed in the myocardial injury group compared to the non-myocardial group across all five days.
- No significant differences were found in mechanical ventilation needs, ICU length of stay, or mortality between the groups.
- HRV indices were markedly altered in COVID-19 patients who developed myocardial injury.
Conclusions:
- HRV indices are significantly impacted in COVID-19 patients experiencing myocardial injury.
- HRV measurements show potential for early detection of cardiac complications in severe COVID-19.
- Further research can explore HRV's role in managing COVID-19-related cardiac conditions.
Background:
Heart rate variability (HRV) is a valuable indicator of autonomic nervous system integrity and can be a prognostic tool of COVID-19 induced myocardial affection. This study aimed to compare HRV indices between patients who developed myocardial injury and those without myocardial injury in COVID-19 patients who were admitted to intensive care unit (ICU).
Methods:
In this retrospective study, the data from 238 COVID-19 adult patients who were admitted to ICU from April 2020 to June 2021 were collected. The patients were assigned to myocardial injury and non-myocardial injury groups. The main collected data were R-R intervals, standard deviation of NN intervals (SDANN) and the root mean square of successive differences between normal heartbeats (RMSSD) that were measured daily during the first five days of ICU admission.
Results:
The R-R intervals, the SDANN and the RMSSD were significantly shorter in the myocardial injury group than the non-myocardial group at the first, t second, third, fourth and the fifth days of ICU admission. There were no significant differences between the myocardial injury and the non-myocardial injury groups with regard the number of patients who needed mechanical ventilation, ICU length of stay and the number of ICU deaths.
Conclusions:
From the results of this retrospective study, we concluded that the indices of HRV were greatly affected in COVID-19 patients who developed myocardial injury.
More Related Videos
05:48Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
Published on: September 21, 2018
14:28Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver
Published on: June 27, 2025
Related Concept Videos
01:30Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
01:27Myocarditis II: Clinical Features and Diagnostic Tests
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
01:19Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
01:25Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
01:14Myocarditis III: Medical Management