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CRISPR/Cas9-guided knockout of eIF4E improves Wheat yellow mosaic virus resistance without yield penalty

Jinhong Kan1, Yu Cai1, Chunyuan Cheng1

  • 1Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China.

Plant Biotechnology Journal
|January 11, 2023
PubMed
Abstract

No abstract available in PubMed .

Keywords:
barley (Hordeum vulgare)eIF4Egenetic resistancegenome editinghost factorwheat (Triticum aestivum)

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CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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