Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.5K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-World Outcomes with BCMA- and GPRC5D-Targeting Bispecific Antibodies in Plasma Cell Leukemia.

Blood advances·2026
Same author

Special issue: Quantitative and precise measurements in conventional (scanning) electron microscopy and electron tomography.

Micron (Oxford, England : 1993)·2026
Same author

A tragedy after successful endovascular intervention; a complication of suture-mediated closure and repair system.

Cardiovascular intervention and therapeutics·2026
Same author

Combined use of drug-eluting stent and drug-coated balloon for tandem lesion with spontaneously recanalized coronary thrombus: insights from optical coherence tomography.

European heart journal. Case reports·2026
Same author

Dual Intracardiac Thromboses Associated With Dilated Coronary Sinus and Persistent Left Superior Vena Cava.

JACC. Case reports·2026
Same author

Reproducibility and Validity of a Food Intake Survey Developed for Implementation via Digital Health for Patients With or at Risk for Cardiovascular Disease.

Circulation reports·2025

Related Experiment Video

Updated: Aug 14, 2025

Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals
10:35

Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals

Published on: May 29, 2018

8.8K

Time-resolved electron holography and its application to an ionic liquid specimen.

Yoh Iwasaki1, Zentaro Akase2, Keiko Shimada1

  • 1Center for Emergent Matter Science, Institute of Physical and Chemical Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

Microscopy (Oxford, England)
|January 11, 2023
PubMed
Summary

Time-resolved electron holography captures dynamic electric polarization in materials. This technique reveals how ionic liquids respond to electric fields, showing limitations in screening high-frequency fields.

Keywords:
electron holographyionic conductorpump probestroboscopictime resolutiontransmission electron microscopy

More Related Videos

Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice
08:31

Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice

Published on: July 20, 2022

3.2K
Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy
07:37

Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy

Published on: December 20, 2012

12.8K

Related Experiment Videos

Last Updated: Aug 14, 2025

Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals
10:35

Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals

Published on: May 29, 2018

8.8K
Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice
08:31

Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice

Published on: July 20, 2022

3.2K
Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy
07:37

Revealing Dynamic Processes of Materials in Liquids Using Liquid Cell Transmission Electron Microscopy

Published on: December 20, 2012

12.8K

Area of Science:

  • Materials Science
  • Condensed Matter Physics
  • Electron Microscopy

Background:

  • Understanding dynamic polarization in materials is crucial for electronic device development.
  • Conventional methods struggle to probe fast polarization responses at the nanoscale.
  • Transmission electron microscopy (TEM) offers high spatial resolution but typically lacks temporal resolution for dynamic processes.

Purpose of the Study:

  • To develop and demonstrate a time-resolved electron holography technique for observing dynamic electric polarization.
  • To investigate the frequency-dependent response of electric polarization in an ionic liquid.
  • To establish the capability of this method for determining the dynamic response limits of materials.

Main Methods:

  • Implementation of time-resolved electron holography in a transmission electron microscope using electron beam gating.
  • Utilized a parallel-plate electrostatic deflector for precise beam control.
  • Performed stroboscopic observations by accumulating gated interference images under a periodic modulation voltage (10 kHz).

Main Results:

  • Successfully observed electric polarization in an ionic liquid specimen under applied electric fields.
  • Demonstrated that static electric fields are screened by material polarization.
  • Showed that a 10 kHz modulated electric field is not screened, indicating a limit in the material's dynamic response.

Conclusions:

  • Time-resolved electron holography is a viable technique for probing dynamic polarization phenomena in materials.
  • The study highlights the frequency-dependent screening behavior of electric fields in ionic liquids.
  • This method provides a powerful tool for characterizing the dynamic response limits of materials relevant to high-frequency applications.