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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
[Physiologic hyperpigmentation on darker skin]
Andreas Glauner1, Esther von Stebut2
1Klinik und Poliklinik für Dermatologie und Venerologie, Uniklinik Köln, Medizinische Fakultät, Universität zu Köln, Kerpener Str. 62, 50935, Köln, Deutschland.
Abstract:
Many, even common, normal variations and nuances of skin of color are less frequently described or often misinterpreted as pathological. Recognizing these physiologic changes is gaining relevance in our increasingly diverse patient population and enables the physician to encourage the acceptance by the patients as well as to manage our resources wisely. Therefore, we explain common hyperpigmentation on dark skin such as demarcation lines, mucosal hyperpigmentation, melanonychia striata, and circumscribed dermal melanocytosis. The aim of this article is to facilitate the classification of these phenomena in clinical practice.
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