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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Contemporary issues in the surgical management of pleural mesothelioma
Juuso Paajanen1, Michael T Jaklitsch1, Raphael Bueno1
1Division of Thoracic Surgery, The Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Lung Center, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.
Abstract:
The surgical management of pleural mesothelioma (PM) can be divided into diagnostic, staging, palliation, and cytoreductive surgery. In the cytoreductive surgical setting, the combination of different treatment modalities has led to better outcomes than surgery alone. The scarcity of high-quality studies has led to heterogeneity in management of PM across the mesothelioma treatment centers. Here, we review the literature regarding the most important open questions and ongoing clinical trials.
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