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Author Spotlight: Demonstrating Systematic Endobronchial Ultrasound to New Endoscopists
Published on: August 11, 2023
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Endobronchial valves: 1st Multicenter retrospective study on the 2-step approach
Thomas Egenod1, Nicolas Guibert2, Yoann Ammar3
1Pulmonology Department, Limoges University Hospital, France.
Respiratory Medicine and Research
|January 11, 2023
Summary
A two-step approach for placing endobronchial valves (EBV) significantly reduced pneumothorax complications in severe emphysema patients. This method maintained treatment benefits without increasing other adverse events, suggesting a safer alternative.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Medical Devices
Background:
- Endobronchial valves (EBV) are used for severe emphysema.
- Pneumothorax is a significant complication of EBV treatment.
- Reducing pneumothorax risk is crucial for improving EBV therapy.
Purpose of the Study:
- To evaluate if a two-step EBV placement reduces pneumothorax frequency.
- To determine if the two-step approach impacts EBV treatment efficacy.
- To compare pneumothorax rates between one-step and two-step EBV procedures.
Main Methods:
- Retrospective study in 15 French pulmonology departments.
- Patients met 2019 Endoscopic Lung Volume Reduction (ELVR) criteria.
- Two-step EBV placement: initial occlusion followed by valve placement one month later.
Main Results:
- 96 patients received EBV treatment between March 2019 and December 2020.
- 12.5% of patients experienced pneumothorax (lower than expected).
- Significant improvements observed in FEV1, RV, 6MWT, BODE Score, and mMRC scale.
Conclusions:
- Two-step EBV placement decreases pneumothorax without compromising efficacy.
- This approach appears to be a safer alternative for severe emphysema treatment.
- Further confirmation via a prospective, randomized controlled study is recommended.
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