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Cardiovascular risk factors in diabetic patients with and without metabolic syndrome: a study based on the Rafsanjan

Gholamreza Bazmandegan1,2, Mitra Abbasifard3,4, Ali Esmaeili Nadimi3,4

  • 1Clinical Research Development Unit, Ali-Ibn Abi-Talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Scientific Reports
|January 11, 2023
PubMed

Insights

Cardiovascular disease (CVD) risk factors are highly prevalent in people with diabetes mellitus (DM). Metabolic syndrome (MtS) affects 80% of diabetic patients, with smoking and alcohol consumption linked to its development.

Area of Science:

  • Endocrinology
  • Cardiology
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a major cause of death in diabetes mellitus (DM).
  • Identifying CVD risk factors in diabetic patients is crucial for prevention.
  • Metabolic syndrome (MtS) is common in DM and linked to increased CVD risk.

Purpose of the Study:

  • To determine the prevalence of cardiovascular risk factors in diabetic individuals with and without metabolic syndrome (MtS).
  • To identify factors associated with metabolic syndrome in a diabetic population.

Main Methods:

  • Cross-sectional study within the Rafsanjan Cohort Study (Persian Cohort).
  • Inclusion of 35-70-year-old adults with and without DM and MtS.
  • Data collection on CVD risk factors via questionnaire; analysis using SPSS v.22.

Main Results:

  • Prevalence of metabolic syndrome (MtS) was 80% (95% CI: 78.1-81.8%) in the studied diabetic population.
  • Logistic regression identified smoking, alcohol consumption, and triglycerides as factors associated with MtS.
  • High prevalence of cardiovascular risk factors was observed in individuals with DM.

Conclusions:

  • Metabolic syndrome is highly prevalent in people with diabetes mellitus.
  • Smoking, alcohol consumption, and elevated triglycerides are associated with metabolic syndrome in this population.
  • Interventions targeting smoking cessation, reduced alcohol intake, and management of hypertension, hyperlipidemia, and obesity are recommended.

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