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Patterns of Dyslipidemia Among Acute Coronary Syndrome (ACS) Patients at a Tertiary Care Hospital in Lahore, Pakistan

Muhammad Muneeb1, Ammar H Khan2, Attaullah Khan Niazi3

  • 1Cardiology, Shalamar Medical and Dental College, Lahore, PAK.

Cureus
|January 12, 2023
PubMed

Insights

Dyslipidemia, an abnormality in lipid levels, is highly prevalent in acute coronary syndrome (ACS) patients, affecting over 83%. This global cardiovascular disease risk factor was more common in males and those with ST-segment elevation myocardial infarction.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Public Health

Background:

  • Dyslipidemia, characterized by abnormal lipid parameters, poses a significant global risk for cardiovascular diseases (CVDs).
  • Understanding the prevalence and patterns of dyslipidemia in acute coronary syndrome (ACS) is crucial for risk stratification and management.

Purpose of the Study:

  • To investigate the prevalence and specific patterns of dyslipidemia among patients diagnosed with acute coronary syndrome (ACS).

Main Methods:

  • A cross-sectional study design was employed.
  • Data were collected from 101 patients admitted with ACS to the critical care unit (CCU) / Rasheeda Begum Cardiac Centre (RBCC) over a 12-month period.
  • Dyslipidemia was diagnosed based on abnormal lipid profile readings.

Main Results:

  • The overall prevalence of dyslipidemia among ACS patients was high, at 83.2%.
  • Dyslipidemia was more prevalent in male patients (65%) compared to female patients (34.5%).
  • Prevalence varied by ACS type: 90.7% in ST-segment elevation myocardial infarction (STEMI), 80.6% in unstable angina (USA), and 74.1% in non-ST segment elevation myocardial infarction (NSTEMI).

Conclusions:

  • A high prevalence of dyslipidemia exists within the ACS patient population.
  • Obesity was also noted as a common comorbidity.
  • Dyslipidemia was found to be more frequent in overweight individuals within this cohort.
Abstract

Keywords:
acute coronary syndromedyslipidemiahigh-density lipoprotein cholesterolmyocardial infarctiontriglycerideunstable angina

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