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Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
Published on: July 24, 2021
A call to action-stopping antimicrobial resistance
Robert W Eisinger1, Mark P Williams1, Sung Hee Choe1
1FasterCures, Milken Institute, 730 15th Street, Washington, DC 20005, USA.
Antimicrobial resistance is a global health crisis. Applying COVID-19 pandemic lessons can accelerate new treatments, diagnostics, and vaccines to combat drug-resistant pathogens.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Antimicrobial resistance (AMR) is a critical public health emergency.
- AMR poses a significant threat, comparable to an impending pandemic.
- Drug-resistant pathogens cause substantial morbidity and mortality worldwide.
Purpose of the Study:
- To emphasize the urgent need for action against antimicrobial resistance.
- To highlight the importance of leveraging lessons from the COVID-19 pandemic response.
- To advocate for a global, collaborative effort to combat AMR.
Main Methods:
- Review and synthesis of lessons learned from the COVID-19 pandemic.
- Analysis of current strategies and challenges in antimicrobial development.
- Identification of key stakeholder roles in a global response.
Main Results:
- The COVID-19 response provides a model for accelerating development of new antimicrobials, diagnostics, and vaccines.
- A coordinated global effort is crucial for success.
- Stakeholder collaboration across sectors is essential.
Conclusions:
- Implementing COVID-19 pandemic response strategies can accelerate the fight against antimicrobial resistance.
- A unified, collaborative global approach is necessary to halt the spread of AMR.
- Preventing further deaths from drug-resistant infections requires immediate, concerted action.
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