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Recognizing neonatal refeeding syndrome and thiamin supplementation: A case report
Caitlin Bradley1, Anne Hansen2, Philip Levy2
1Department of Nursing, Boston Children's Hospital, Boston, Massachusetts, USA.
JPEN. Journal of Parenteral and Enteral Nutrition
|January 12, 2023
Summary
Refeeding syndrome (RS) can occur in newborns after nutritional support, causing dangerous electrolyte imbalances. Early thiamin treatment is suggested for suspected neonatal RS cases, especially after therapeutic hypothermia.
Area of Science:
- Neonatology
- Pediatric Critical Care
- Nutritional Support
Background:
- Refeeding syndrome (RS) guidelines are established for adults and children.
- Limited newborn-specific guidelines exist due to scarce literature and varied reporting.
Observation:
- A small-for-gestational-age newborn with neonatal encephalopathy received therapeutic hypothermia.
- Electrolyte derangements and lactic acidosis persisted despite intravenous nutrition.
Findings:
- Neonatal RS was suspected after excluding other causes.
- The newborn improved with thiamin treatment.
Implications:
- This case highlights the potential for neonatal RS.
- Suggests thiamin replacement may be beneficial for suspected neonatal RS.
- Underscores the need for more research into neonatal RS.
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