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Morphometry of nuclear rings at high electron microscopic resolution.
1University of Granada, Spain.
Analytical and Quantitative Cytology and Histology
|August 1, 1987
Summary
A novel nuclear ring organelle was discovered, exhibiting torus-like geometry. Morphologic measurements reveal stable thickness and connections to chromatin, suggesting a crucial cellular role.
Area of Science:
- Cell Biology
- Nuclear Structure
- Electron Microscopy
Background:
- The nuclear chromatin's fine structure is complex.
- Understanding nuclear components is crucial for cell function.
Purpose of the Study:
- To describe a newly discovered nuclear organelle, the nuclear ring.
- To analyze the morphologic characteristics of isolated nuclear rings.
Main Methods:
- Electron microscopy was used.
- Morphologic measurements of 424 isolated nuclear rings were performed.
- Geometric features were calculated from inner and outer diameters.
Main Results:
- A novel organelle, the nuclear ring, was identified.
- Rings varied fivefold in size, with correlated inner and outer diameters.
- Stable ring thickness was inferred from diameter correlations.
Conclusions:
- The nuclear ring's significance is currently unclear.
- Its connections to chromatin and the nuclear envelope suggest a vital role.
- The findings challenge the concept of patent nuclear pores.