Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Molecular Models02:00

Molecular Models

39.2K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
39.2K
Molecular Compounds01:24

Molecular Compounds

3
Molecular CompoundsMolecular compounds form when two or more nonmetal atoms share electrons through covalent bonds. Unlike ionic compounds, where electrons are transferred, molecular compounds remain electrically neutral because electrons are shared equally or unequally between atoms.Common Examples of Molecular Compounds:Water (H₂O): Essential for life; it forms hydrogen bonds that give it unique properties.Carbon dioxide (CO₂): A gas used by plants in photosynthesis.Methane (CH₄): A...
3
Atoms and Molecules01:24

Atoms and Molecules

2
Atoms and MoleculesEverything around us is made of tiny particles called atoms. Atoms are the smallest units of matter and are the building blocks of all substances. When atoms bond together, they form molecules, which make up solids, liquids, and gases. Understanding atoms and molecules helps scientists explain how different substances interact and change in both physical and chemical processes.Science and Engineering Practices (SEP): Developing and Using ModelsScientists use models to...
2
Molecular Shapes01:18

Molecular Shapes

57.2K
Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.
Two regions of electron density in a diatomic...
57.2K
MO Theory and Covalent Bonding02:40

MO Theory and Covalent Bonding

10.7K
The molecular orbital theory describes the distribution of electrons in molecules in a manner similar to the distribution of electrons in atomic orbitals. The region of space in which a valence electron in a molecule is likely to be found is called a molecular orbital. Mathematically, the linear combination of atomic orbitals (LCAO) generates molecular orbitals. Combinations of in-phase atomic orbital wave functions result in regions with a high probability of electron density, while...
10.7K
Classification of Elements and Compounds02:54

Classification of Elements and Compounds

67.1K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units.
Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
67.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rising dust pollution across Europe in a changing climate.

Nature·2026
Same author

Plasma-SELEX for Acute Myocardial Infarction Biomarker Discovery and Diagnosis.

Analytical chemistry·2026
Same author

Efficient removal of heavy metal Cr(vi) from wastewater <i>via</i> synergy of defect engineering and S-scheme heterojunction.

RSC advances·2026
Same author

Joint Impact of Triglyceride-glucose Index and Free Fatty Acid Levels on Cardiovascular Outcomes in Overweight or Obese Patients with Coronary Artery Disease - A Large Multicenter Prospective Study.

Biomedical and environmental sciences : BES·2026
Same author

Reprogramming Aromatic Camptothecins into TOP1 Degraders via Synergistic Hydrophobic Tagging and Supramolecular Assembly.

Journal of the American Chemical Society·2026
Same author

Author Correction: DNA nanodevices detect an acidic nanolayer on the lysosomal surface.

Nature cell biology·2026

Related Experiment Video

Updated: Aug 14, 2025

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.1K

Molecular elements: novel approaches for molecular building.

Ruowen Wang1,2,3, Xueqiang Wang4,2, Sitao Xie4,2

  • 1Institute of Molecular Medicine (IMM), Renji Hospital, School of Medicine, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200127, People's Republic of China.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|January 12, 2023
PubMed
Summary

This review redefines molecular elements (MEs) as synthetic oligonucleotides (ONs) for creating designer molecules and smart materials. This concept is crucial for developing ON therapeutics targeting genetic errors.

Keywords:
aptamermolecular elementnucleic acid therapeuticsoligonucleotideunnatural base

More Related Videos

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

3.0K
Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis
07:24

Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis

Published on: May 10, 2021

6.3K

Related Experiment Videos

Last Updated: Aug 14, 2025

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.1K
Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

3.0K
Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis
07:24

Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis

Published on: May 10, 2021

6.3K

Area of Science:

  • Chemical Biology
  • Synthetic Biology
  • Materials Science

Background:

  • Traditional definition of molecular elements (MEs) as pure substances.
  • Expansion of the ME concept to include synthetic oligonucleotides (ONs) with designed sequences and functions.
  • Inclusion of natural and unnatural bases within the ME framework.

Purpose of the Study:

  • To redefine and focus on the molecular element (ME) concept for synthetic oligonucleotides (ONs).
  • To highlight the role of MEs in the synthesis of designer molecules and smart materials.
  • To discuss the application of ONs in therapeutic interventions for genetic disorders.

Main Methods:

  • Review of landmarks in DNA structure and related technologies.
  • Discussion of the extensive applications of oligonucleotides (ONs).
  • Focus on the ME concept for fabricating molecules and nanostructures.

Main Results:

  • Molecular elements (MEs) are redefined to encompass synthetic oligonucleotides (ONs).
  • Oligonucleotides (ONs) are identified as ideal molecules for intervention therapy against genetic errors.
  • The ME concept is foundational for discovering ON therapeutics and fabricating designer molecules.

Conclusions:

  • The ME concept is pivotal for advancing synthetic biology and materials science.
  • Oligonucleotide therapeutics and designer molecule fabrication rely on the ME concept.
  • Future research directions and perspectives in molecule and material fabrication are discussed through the ME lens.