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Gastric Emptying

Gastric Emptying

Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...

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Related Experiment Video

Updated: Aug 14, 2025

Sleeve Gastrectomy in Mice using Surgical Clips

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Intragastric Balloon Significantly Improves Metabolic Parameters at 6 Months: a Meta-Analysis.

Rahil H Shah¹, Shyam Vedantam¹, Shria Kumar²

¹Department of Medicine, University of Miami, Miami, FL, USA.

Obesity Surgery

|January 12, 2023

Summary

Intragastric balloons (IGBs) significantly improve key health markers like A1c, blood pressure, and cholesterol levels within six months. This obesity treatment offers metabolic benefits beyond just weight loss.

Keywords:

Bariatric therapy Diabetes Hyperlipidemia Hypertension Intragastric balloon Metabolic syndrome

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Last Updated: Aug 14, 2025

Sleeve Gastrectomy in Mice using Surgical Clips

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Published on: November 14, 2020

A Murine Model of Vertical Sleeve Gastrectomy

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Published on: December 18, 2017

One-anastomosis Gastric Bypass OAGB in Rats

One-anastomosis Gastric Bypass OAGB in Rats

Published on: November 10, 2018

Area of Science:

Metabolic health
Bariatric interventions
Obesity management

Background:

Rising global obesity rates necessitate effective treatment strategies.
Intragastric balloons (IGBs) offer a minimally invasive option for obesity management.
The impact of IGBs on metabolic parameters requires comprehensive evaluation.

Approach:

A systematic meta-analysis was conducted using data from PubMed, Embase, and Google Scholar.
17 studies involving 1198 patients were analyzed to assess IGB therapy outcomes at 6 months.
Pooled results from a random-effects model were used to determine treatment effects.

Key Points:

IGB therapy led to significant reductions in hemoglobin A1c (A1c), systolic and diastolic blood pressure (SBP, DBP).
Significant improvements were observed in total cholesterol (TC), LDL cholesterol (LDL), and triglycerides (TGs).
No significant changes were noted in HDL cholesterol levels post-IGB insertion.

Conclusions:

IGB therapy demonstrates efficacy in improving insulin resistance, blood pressure, and lipid profiles.
IGB placement presents a viable option for enhancing metabolic health in patients with obesity.
The benefits extend beyond weight reduction, positively impacting crucial metabolic indicators.