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Malignant hyperpyrexia and isoflurane. A case report
D W Thomas1, V J Dev, M J Whitehead
1Department of Anaesthetics, Morriston Hospital, Cwmrhydyceirw, Swansea.
British Journal of Anaesthesia
|September 1, 1987
Abstract:
Malignant hyperpyrexia developed, and was successfully treated, in a 50-year old man undergoing pyelolithotomy. Early diagnosis with the assistance of end-tidal carbon dioxide monitoring facilitated prompt treatment with i.v. dantrolene. A positive muscle biopsy subsequently confirmed the diagnosis. The only likely triggering agent used was isoflurane.