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Related Experiment Video

Updated: Aug 14, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Migraine in childhood: Gender differences.

Fabiana Ursitti1, Massimiliano Valeriani1

  • 1Developmental Neurology Unit, Ospedale Pediatrico Bambino Gesù, Rome, Italy.

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
|January 12, 2023
PubMed
Summary
This summary is machine-generated.

Gender and age significantly influence childhood migraine, with differences observed in epidemiology and clinical presentation. Further research is needed to fully understand these pediatric migraine variations, particularly around puberty.

Keywords:
AdolescentsChildrenDevelopmental ageMigrainePuberty

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Area of Science:

  • Neurology
  • Pediatrics
  • Epidemiology

Background:

  • Migraine affects up to 20% of children and adolescents, presenting as a common neurological disorder.
  • Gender differences in adult migraine are well-documented, but less understood in pediatric populations.

Purpose of the Study:

  • To provide an overview of gender differences in pediatric migraine.
  • To synthesize current knowledge on epidemiological, pathophysiological, and clinical variations between genders in children and adolescents.

Main Methods:

  • A review of the most recent scientific literature was conducted.
  • The review focused on identifying and analyzing gender and age-related differences in childhood migraine.

Main Results:

  • Epidemiological and clinical characteristics of migraine in children and adolescents show variations based on gender.
  • Age and pubertal development appear to be key factors influencing these gender-related differences.

Conclusions:

  • Childhood migraine syndrome exhibits gender and age-specific variations.
  • Pubertal development is a critical factor requiring further investigation in the context of gender differences in pediatric migraine.