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Updated: Aug 14, 2025

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV

Published on: September 14, 2010

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The Kaposi's sarcoma progenitor enigma: KSHV-induced MEndT-EndMT axis

Julian Naipauer1, Enrique A Mesri2

  • 1Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina; Tumor Biology Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA; University of Miami- Center for AIDS Research (UM-CFAR)/Sylvester Comprehensive Cancer Center (CCC) Argentina Consortium for Research and Training in Virally Induced AIDS-Malignancies, University of Miami Miller School of Medicine, Miami, FL, USA; Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

Trends in Molecular Medicine
|January 12, 2023
PubMed
Summary

Kaposi's sarcoma herpes virus (KSHV) drives endothelial-to-mesenchymal transition in progenitor cells, revealing a key mechanism in cancer development and a potential therapeutic target.

Keywords:
Kaposi´s sarcoma herpesvirusangiogenesisendothelial-to-mesenchymal differentiation axissarcomagenesisvirus oncogenesis

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