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Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development

Changuk Chung1,2, Xiaoxu Yang1,2, Taejeong Bae3

  • 1Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.

Nature Genetics
|January 12, 2023
PubMed
Summary

Researchers identified 69 mutated genes linked to malformations of cortical development (MCD), a neurological condition causing epilepsy. This discovery advances understanding of brain development disorders and their genetic underpinnings.

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