Bullous Pilomatrixoma After COVID-19 Vaccination

Area of Science:

• Dermatology
• Pediatric Oncology

Background:

• Pilomatrixoma, a common childhood epithelial tumor, arises from hair matrix cells.
• Bullous pilomatrixoma is an exceptionally rare variant, typically affecting upper extremities and linked to trauma.

Observation:

• A case of bullous pilomatrixoma presented as a rapidly growing neoformation.
• The lesion appeared one month post-coronavirus disease 2019 (COVID-19) vaccination in the left upper arm.

Findings:

• The study details a unique presentation of bullous pilomatrixoma.
• The rapid growth post-vaccination raises questions about potential triggers or associations.

Implications:

• This case highlights a rare pilomatrixoma variant and its potential association with recent vaccination.
• Further investigation is warranted to understand the relationship between the bullous presentation, tumor biology, and potential secondary anetoderma.