Related Experiment Video
Updated: Aug 14, 2025
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Diagnosis and Management of Allergic Rhinitis in Asthmatic Children
Laura Tenero1, Rachele Vaia2, Giuliana Ferrante1
1Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Clinic, University of Verona, Verona, Italy.
Insights
Allergic rhinitis (AR) in children significantly impacts quality of life and is a major risk factor for asthma development. Allergen immunotherapy (AIT) offers a personalized approach to manage AR and improve asthma control.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
- Clinical Immunology
Background:
- Allergic rhinitis (AR) is a prevalent inflammatory condition in children, affecting quality of life, sleep, and daily functioning.
- AR is a significant risk factor for the onset of pediatric asthma and a key determinant of asthma control.
- The interplay between AR and asthma in pediatric populations necessitates a comprehensive management strategy.
Purpose of the Study:
- To provide an updated overview of allergic rhinitis epidemiology and diagnosis in children.
- To emphasize the strong connection between allergic rhinitis and pediatric bronchial asthma.
- To highlight the role of allergen immunotherapy (AIT) as a precision medicine approach for managing AR and its impact on asthma.
Main Methods:
- Review of current literature on allergic rhinitis and its association with bronchial asthma in pediatric populations.
- Analysis of epidemiological data and diagnostic approaches for AR.
- Evaluation of allergen immunotherapy (AIT) as a treatment modality within a precision medicine framework.
Main Results:
- Allergic rhinitis is a critical risk factor for asthma development in children.
- AR significantly influences asthma control, acting as an extra-bronchial determinant.
- Allergen immunotherapy (AIT) presents a unique opportunity to address the immunological underpinnings of AR and improve outcomes for both AR and asthma.
Conclusions:
- Physicians managing pediatric AR, especially when co-occurring with asthma, should prioritize assessing patient eligibility for AIT.
- AIT, viewed through a precision medicine lens, can specifically target AR's immunological basis.
- Implementing AIT can lead to improved control of both allergic rhinitis and bronchial asthma, potentially preventing disease progression.
Abstract:
Allergic rhinitis (AR) is a common upper airways inflammatory condition especially in paediatric population; its burden potentially impacts on quality of life, quality of sleep and daily performance, which can be difficult to perceive but not less relevant in the middle-long term. The present review aims to provide an updated overview on AR epidemiology, diagnosis and with a special focus on its connections with bronchial asthma. In fact, when considering asthmatic pediatric population, AR is probably the most important risk factor for asthma onset and the most impactful extra-bronchial determinant of asthma control. Under this perspective, allergen immunotherapy (AIT) should always be considered in the light of a precision medicine approach. In fact, AIT does represent a unique opportunity to specifically interfere with AR immunological background, improve both AR and bronchial asthma control and prevent allergic disease evolution. Verifying the patient's eligibility to that option should be considered as a priority for every physician managing children suffering from AR, especially when associated with bronchial asthma.
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