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Updated: Aug 14, 2025

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IDH2 stabilizes HIF-1α-induced metabolic reprogramming and promotes chemoresistance in urothelial cancer

Keisuke Shigeta1, Masanori Hasegawa2, Takako Hishiki3,4

  • 1Department of Urology, Keio University School of Medicine, Tokyo, Japan.

The EMBO Journal
|January 13, 2023
PubMed

Keywords:
chemoresistancehypoxia-inducible factor-1αisocitrate dehydrogenase 2metabolomic reprogrammingurothelial carcinoma

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