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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Postpartum Psychosis.
Susan Hatters Friedman1, Eric Reed2, Nina E Ross2
1Case Western Reserve University, 10254 Euclid Avenue, Cleveland, OH, 44106, USA. SJH8@Case.edu.
Postpartum psychosis (PPP) is a serious psychiatric emergency requiring specialized care. Understanding its unique pathways and considering the whole family is key for effective diagnosis and treatment.
Area of Science:
- Psychiatry
- Obstetrics
- Perinatal Mental Health
Background:
- Postpartum psychosis (PPP) presents a critical psychiatric emergency impacting mothers, infants, and families.
- PPP is distinct from general psychosis, necessitating specific research and understanding for effective management.
Purpose of the Study:
- To review the latest research findings on postpartum psychosis (PPP).
- To update clinicians and researchers on the current evidence base for PPP identification, treatment, and prevention.
Main Methods:
- Literature review of recent research findings on postpartum psychosis.
- Synthesis of evidence regarding pathophysiological pathways and clinical implications.
Main Results:
- Physiologic pathways implicated in PPP development offer potential for early detection and treatment.
- Risk assessment and treatment strategies must encompass the mother-infant dyad and family unit.
Conclusions:
- Updated research on postpartum psychosis can inform clinical practice.
- Promoting specialized, evidence-based diagnosis, risk assessment, and treatment for PPP is crucial.
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