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Updated: Aug 14, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Ocular Involvement of Brucellosis: A Pooled Analysis Study
Oğuz Evlice1, Sevil Alkan Çeviker2, Armağan Filik3
1Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Kutahya Health Sciences University, Kütahya, Turkey.
Aim:
Brucellosis may affect the eye to varying degrees. The aim of this study was to investigate the ocular involvement of brucellosis and highlight key points.
Material And Methods:
Published literature in English language on the ocular involvement of brucellosis within last 30 years was evaluated. The PubMed international database was screened using certain keywords.
Results:
The study included 27 publications evaluating a total of 159 cases. The most common types of ocular involvement were uveitis (52.2%) and conjunctivitis (17.6%). Most cases had concomitant systemic brucellosis (27.7%), and the most commonly used diagnostic method was a serological test (92.4%). Of all the patients, 37.1% recovered with sequelae.
Conclusion:
Brucellosis may cause a wide range of ophthalmic manifestations, and an overlooked or late diagnosis may also lead to the development of sequelae or loss of vision. A routine ophthalmologic examination should be performed in all patients with systemic brucellosis.
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