Related Experiment Video
Updated: Aug 14, 2025

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
Published on: February 1, 2022
Diagnosis and management of arrhythmogenic right ventricular cardiomyopathy
Leen Alblaihed1, Christine Kositz2, William J Brady3
1Department of Emergency Medicine, University of Maryland School of Medicine, 110 S Paca Street, 6(th) Floor, Suite 200, Baltimore, MD 21201, United States of America.
Insights
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic heart condition causing dangerous arrhythmias and sudden death, especially in young athletes. Early diagnosis by emergency clinicians is vital for preventing fatalities.
Area of Science:
- Cardiology
- Genetics
- Internal Medicine
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic myocardial disorder.
- It is a leading cause of sudden cardiac death in young individuals and athletes.
- Early recognition by emergency clinicians is critical for preventing mortality.
Purpose of the Study:
- To review the pathophysiology of ARVC.
- To outline the classification and clinical presentations of ARVC.
- To describe the diagnostic and management strategies for ARVC.
Main Methods:
- Literature review on ARVC.
- Synthesis of information on pathophysiology, classification, clinical features, diagnosis, and management.
- Systematic approach to diagnosis and management.
Main Results:
- ARVC presents a diagnostic challenge requiring a systematic approach.
- Understanding pathophysiology, classification, and clinical presentation aids diagnosis.
- Appropriate management strategies are crucial for patient outcomes.
Conclusions:
- ARVC is a significant cause of sudden cardiac death.
- Early and accurate diagnosis is essential for effective management.
- A systematic approach improves the identification and treatment of ARVC.
Abstract:
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic disorder of the myocardium that can lead to ventricular arrhythmia and sudden cardiac death. The condition has been identified as a significant cause of arrhythmic death among young people and athletes, therefore, early recognition of the disease by emergency clinicians is critical to prevent subsequent death. The diagnosis of ARVC can be very challenging and requires a systematic approach. This publication reviews the pathophysiology, classification, clinical presentations, and appropriate approach to diagnosis and management of ARVC.
Related Concept Videos
Cardiomyopathy IV: Restrictive Cardiomyopathy
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy I: Introduction and Classification
Dysrhythmias V: Evaluating Dysrhythmias

