Decrease of natalizumab drug levels after switching from intravenous to subcutaneous administration in patients with

Alyssa A Toorop1, Zoé L E van Kempen2, Maurice Steenhuis3

  • 1Department of Neurology, MS Center Amsterdam, Amsterdam UMC Location VUMC, Amsterdam, The Netherlands a.toorop@amsterdamumc.nl.

Summary

Switching to subcutaneous natalizumab may lower drug levels in multiple sclerosis patients. Monitoring natalizumab trough levels is advised for those on extended intervals or with specific patient factors after switching administration routes.

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