Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethics in Research01:56

Ethics in Research

23.1K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.1K
Ethics and Bioethics01:22

Ethics and Bioethics

1.5K
Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
1.5K
Ethical Dilemmas I01:17

Ethical Dilemmas I

998
Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
998
Ethical Issues01:27

Ethical Issues

1.1K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.1K
Ethical Dilemmas II01:30

Ethical Dilemmas II

1.2K
Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
1.2K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

156
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
156

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technology and the clinical encounter: a qualitative study of mental health clinician and patient experiences of telemedicine.

BMC health services research·2026
Same author

Paediatric Nurses' Decision-Making About CPR in Challenging Clinical Scenarios : Insights From a Cross-Sectional Survey.

Journal of bioethical inquiry·2026
Same author

Development of an Ethico-Legal Framework for Quality Improvement and Performance Management in Health Care: Protocol for a Qualitative Study.

JMIR research protocols·2026
Same author

Research prioritization and societal accountability in corporatised healthcare services - What can Responsible Innovation offer?

Accountability in research·2026
Same author

Managing Nonfinancial Conflicts of Interest in Oncology Research-A Guide for Practice.

JAMA oncology·2025
Same author

Improving Consumer Engagement in Health Technology Assessment and Decision Making: Lessons from 'Values in Science'.

Applied health economics and health policy·2025

Related Experiment Video

Updated: Aug 14, 2025

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.3K

Clinical innovation ethics frameworks: A systematic narrative review.

Miriam Wiersma1, Ian Kerridge2, Wendy Lipworth3

  • 1Faculty of Medicine and Health, Sydney School of Public Health, Sydney Health Ethics, Rm 134, Edward Ford Building A27, The University of Sydney, NSW 2006, Australia.

Health Policy (Amsterdam, Netherlands)
|January 13, 2023
PubMed
Summary

Doctors often use novel interventions, termed clinical innovation, believing it benefits patients. However, ethical frameworks for clinical innovation show significant overlap, suggesting a need for harmonized oversight beyond practice-specific exceptionalism.

Keywords:
GovernanceInnovationReview

More Related Videos

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

23.8K
The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups
14:14

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

Published on: May 13, 2022

6.0K

Related Experiment Videos

Last Updated: Aug 14, 2025

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.3K
Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

23.8K
The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups
14:14

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

Published on: May 13, 2022

6.0K

Area of Science:

  • Medical Ethics
  • Clinical Practice
  • Healthcare Innovation

Background:

  • Clinical innovation, the use of novel interventions outside evidence-based standards, is common but poorly defined.
  • Physicians employ clinical innovation believing it benefits patients, despite lacking established safety and efficacy data.
  • Current oversight mechanisms for clinical innovation are fragmented and lack cohesive structure.

Approach:

  • A systematic narrative review was conducted.
  • The review analyzed 47 articles on ethics frameworks for clinical innovation.
  • The aim was to identify commonalities and differences across medical specialties.

Key Points:

  • Ethical issues in clinical innovation are largely consistent across medical specialties.
  • Oversight mechanisms vary but reflect general attitudes (cautious vs. permissive) rather than specialty-specific needs.
  • A tendency exists to treat innovative interventions as exceptional, hindering the development of higher-order ethical frameworks.

Conclusions:

  • Ethics frameworks for clinical innovation demonstrate substantial overlap across diverse practice areas.
  • There's a need to move beyond practice-specific exceptionalism towards harmonized, higher-order ethical frameworks, akin to research ethics.
  • Balancing exceptionalism with harmonization is crucial for effective clinical innovation oversight.