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[Monkeypox: Important facts for the ophthalmologist]
G Hoarau1, C Vauloup Fellous2, O Haigh3
1Service d'ophtalmologie, réseau OPHTARA, CHU Bicêtre Paris-Saclay, université Paris Saclay, AP-HP, Kremlin-Bicêtre, France.
Journal Francais D'Ophtalmologie
|January 13, 2023
Summary
The global monkeypox virus (MPXV) outbreak offers insights into MPXV pathophysiology and management. Ophthalmologists play a key role in diagnosing and treating ocular manifestations, crucial for patient care and preventing transmission.
Area of Science:
- Virology
- Infectious Diseases
- Ophthalmology
Context:
- The 2022 global monkeypox virus (MPXV) outbreak is the largest recorded, highlighting its potential for widespread transmission.
- MPXV, previously a neglected tropical disease endemic in Africa, now demands broader attention due to its global reach and clinical impact.
Purpose:
- To review the pathophysiology, diagnosis, and treatment of MPXV, with a focus on ocular manifestations.
- To define management strategies for severe MPXV disease and discuss prevention of transmission.
- To emphasize the critical role of ophthalmologists in early MPXV diagnosis and ocular management.
Summary:
- Ocular involvement, including conjunctivitis and keratoconjunctivitis, is common in MPXV infections and can be the primary or preceding symptom.
- While typically self-limiting, MPXV keratoconjunctivitis can lead to severe visual impairment, particularly in immunocompromised individuals.
- Ophthalmologists are pivotal in identifying MPXV, managing eye complications, and collaborating on public health measures to curb transmission.
Impact:
- Enhanced understanding of MPXV physiopathology and clinical presentation.
- Improved management strategies for MPXV, especially severe ocular cases.
- Strengthened interdisciplinary collaboration for epidemic control and patient care.
