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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

674
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
674

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Related Experiment Video

Updated: Aug 14, 2025

Organotypic Retinal Explant Cultures from Macaque Monkey
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[Monkeypox: Important facts for the ophthalmologist].

G Hoarau1, C Vauloup Fellous2, O Haigh3

  • 1Service d'ophtalmologie, réseau OPHTARA, CHU Bicêtre Paris-Saclay, université Paris Saclay, AP-HP, Kremlin-Bicêtre, France.

Journal Francais D'Ophtalmologie
|January 13, 2023
PubMed
Summary
This summary is machine-generated.

The global monkeypox virus (MPXV) outbreak offers insights into MPXV pathophysiology and management. Ophthalmologists play a key role in diagnosing and treating ocular manifestations, crucial for patient care and preventing transmission.

Keywords:
ConjonctiviteEpidemyMonkeypoxVirusÉpidémie

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Area of Science:

  • Virology
  • Infectious Diseases
  • Ophthalmology

Context:

  • The 2022 global monkeypox virus (MPXV) outbreak is the largest recorded, highlighting its potential for widespread transmission.
  • MPXV, previously a neglected tropical disease endemic in Africa, now demands broader attention due to its global reach and clinical impact.

Purpose:

  • To review the pathophysiology, diagnosis, and treatment of MPXV, with a focus on ocular manifestations.
  • To define management strategies for severe MPXV disease and discuss prevention of transmission.
  • To emphasize the critical role of ophthalmologists in early MPXV diagnosis and ocular management.

Summary:

  • Ocular involvement, including conjunctivitis and keratoconjunctivitis, is common in MPXV infections and can be the primary or preceding symptom.
  • While typically self-limiting, MPXV keratoconjunctivitis can lead to severe visual impairment, particularly in immunocompromised individuals.
  • Ophthalmologists are pivotal in identifying MPXV, managing eye complications, and collaborating on public health measures to curb transmission.

Impact:

  • Enhanced understanding of MPXV physiopathology and clinical presentation.
  • Improved management strategies for MPXV, especially severe ocular cases.
  • Strengthened interdisciplinary collaboration for epidemic control and patient care.