Related Experiment Video

Updated: Aug 14, 2025

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

12.0K

Analyzing sleep status in children with acute leukemia

Lu Xi1, Guangsheng Wu2, Xinke Du3

  • 1Department of Hematology and Oncology, The Children's Hospital of Zhejiang University School of Medicine, Zhejiang Pediatric Leukemia Diagnosis and Treatment Technology Center, National Pediatric Health and Disease Clinical Medical Research Center, Hangzhou, 310000, Zhejiang, China.

Italian Journal of Pediatrics
|January 13, 2023
PubMed

Insights

Sleep disorders are common in children with acute leukemia, affecting nearly half of those studied. Parental behaviors and airway issues like adenoid hypertrophy significantly influence these sleep problems, increasing parental stress.

Area of Science:

  • Pediatric Oncology
  • Sleep Medicine
  • Child Psychology

Background:

  • Quality sleep is crucial for children's physical and mental well-being.
  • Acute leukemia and its treatment can significantly impact a child's health.
  • Sleep disorders are a potential complication in children undergoing cancer treatment.

Purpose of the Study:

  • To investigate the prevalence of sleep disorders in children diagnosed with acute leukemia.
  • To identify factors associated with sleep disturbances in this pediatric population.
  • To explore the relationship between sleep disorders and parental stress.

Main Methods:

  • A cross-sectional study involving 173 children with acute leukemia undergoing chemotherapy.
  • Data collection using general questionnaires, the Children's Sleep Disorders Scale, and the Parenting Stress Index-short form.
  • Statistical analysis including single- and multi-factor regression to identify influencing factors.

Main Results:

  • Sleep disorders were identified in 45.66% of children with acute leukemia.
  • Factors associated with sleep disorders included parental scolding and adenoid hypertrophy.
  • Children experiencing sleep disorders reported higher levels of parental stress compared to those without.

Conclusions:

  • Sleep disorders are prevalent in children with acute leukemia, linked to airway conditions and parental behaviors.
  • Addressing sleep quality is vital for the recovery and well-being of these children.
  • Interventions should focus on improving sleep hygiene and providing parental support and education.
Abstract

Keywords:
Acute leukemiaAdenoid hypertrophyChildrenScoldingSleep disorders

More Related Videos

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia09:57

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

Published on: March 5, 2018

29.6K
Assessment of the Metabolic Profile of Primary Leukemia Cells06:21

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

10.6K

Related Concept Videos

Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.5K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
205
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
175
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
331
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
192
Nightmares and Night Terrors01:18

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
146