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Related Experiment Videos

Cough and mucociliary clearance.

D Pavia1, J E Agnew, S W Clarke

  • 1Department of Thoracic Medicine, Royal Free Hospital, London, UK.

Bulletin Europeen De Physiopathologie Respiratoire
|January 1, 1987
PubMed
Summary
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Coughing effectively clears lung secretions only in the large airways. For peripheral lung clearance, the forced expiration technique is more effective than coughing.

Area of Science:

  • Respiratory Physiology
  • Pulmonary Medicine
  • Mucociliary Clearance

Background:

  • Cough is a vital defense mechanism for the lungs.
  • Previous research suggests cough's efficacy in secretion clearance is limited to proximal airways.

Purpose of the Study:

  • To evaluate the effectiveness of cough in clearing lung secretions, particularly in peripheral regions.
  • To compare cough efficacy with alternative airway clearance techniques.

Main Methods:

  • Utilized radioaerosols as markers to study mucus transport.
  • Investigated the impact of coughing on regional lung clearance.
  • Compared cough with the forced expiration technique.

Main Results:

Related Experiment Videos

  • Cough is effective for clearing excess secretions primarily in the proximal airways.
  • Evidence for cough's efficacy in peripheral airway clearance remains equivocal.
  • Persistent coughing can temporarily impede lung mucociliary clearance.
  • The forced expiration technique demonstrated superior efficacy in clearing lung secretions compared to coughing.

    • Conclusions:

    • Cough's role in peripheral lung secretion clearance is limited.
    • The forced expiration technique offers a more effective method for airway clearance, especially in the presence of excess secretions.