Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioreactor Design and Operational System

Bioreactor Design and Operational System

Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Germline pathogenic variants associated with prostate cancer susceptibility in a Spanish cohort: emergence of new key players.

Scientific reports·2026

Same author

Microbial modulation of proteoglycan and glycosaminoglycan biosynthesis in a three-dimensional corneal epithelium model.

Frontiers in cellular and infection microbiology·2026

Same author

A miR-200b-Filamin A axis drives epicardial contribution to cardiogenesis.

Scientific reports·2026

Same author

A global survey of systems biology-based predictions of gene-rare disease associations to enhance new diagnoses.

Scientific reports·2026

Same author

Programmable DNA-Based Molecular Reservoir Biocomputing Network Circuits with Emerging Biomemristors for Solving Complex Nonlinear Problems.

ACS synthetic biology·2026

Same author

Correction: Mathematical models and computational approaches in CAR-T therapeutics.

Frontiers in immunology·2025

Same journal

An accessible, absorbance-based plate reader assay to assess cumulative exposure of blood plasma & serum to thawed conditions.

Methods (San Diego, Calif.)·2026

Same journal

EC-isHCR: A rapid method for in situ hybridization chain reaction in diverse animal samples.

Methods (San Diego, Calif.)·2026

Same journal

Single-Molecule methods to investigate mechanisms of transcription by RNA polymerase of Mycobacterium tuberculosis.

Methods (San Diego, Calif.)·2026

Same journal

Detection and sequencing of Usutu virus during mosquito surveillance: Use of multiple assays and techniques for identification at low levels.

Methods (San Diego, Calif.)·2026

Same journal

Experimental validation of an AI-driven digital healthcare platform for oral health behavior and plaque assessment among vietnamese children.

Methods (San Diego, Calif.)·2026

Same journal

Zeta potential: An efficient and cost-effective alternative for investigating cell-surface interactions.

Methods (San Diego, Calif.)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

Published on: October 2, 2012

BioBlocksLab: A portable DIY Bio Lab using BioBlocks language.

Tongmao Ma¹, David Méndez-Merino¹, Graciela Uría-Regojo²

¹Departamento de Inteligencia Artificial, ETSIINF, Universidad Politécnica de Madrid, 28040, Madrid, Spain.

Methods (San Diego, Calif.)

|January 14, 2023

Summary

This summary is machine-generated.

This study introduces BioBlocksLab, an affordable, portable DIY bio-lab. It uses a new programming language, BioBlocks 2.0, to control modular hardware for molecular biology experiments.

Keywords:

BioBlocks BioBlocksLab DIY-bio MakeCode Portable bio-lab

More Related Videos

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

Related Experiment Videos

Last Updated: Jun 17, 2026

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

Published on: October 2, 2012

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

Area of Science:

Molecular Biology
Biotechnology
Open-Source Science

Background:

Standard molecular biology labs rely on expensive, complex equipment, limiting accessibility.
The high cost of traditional labs presents a barrier for many aspiring researchers and educators.
DIY and open-source approaches are emerging to democratize scientific experimentation.

Purpose of the Study:

To develop an affordable and portable modular bio-laboratory system.
To create an intuitive programming interface for controlling laboratory hardware.
To enable accessible molecular biology experimentation for a wider audience.

Main Methods:

Construction of a portable bio-lab, BioBlocksLab, comprising four functional modules: centrifuge, thermocycler, electrophoresis, and incubator.
Development of BioBlocks 2.0, a block-based programming language based on Microsoft MakeCode and PXT, for protocol description.
Execution of real-world molecular biology protocols using BioBlocks 2.0 to control the hardware modules with biological reagents.

Main Results:

Successful operation of the BioBlocksLab system with positive experimental outcomes.
Demonstration of the BioBlocks 2.0 programming language's capability to control diverse hardware modules.
Validation of the system's efficacy in performing standard molecular biology protocols.

Conclusions:

BioBlocksLab provides an accessible, cost-effective solution for molecular biology research and education.
The open-source nature of BioBlocksLab and BioBlocks 2.0 promotes wider adoption and community development.
This DIY portable bio-lab empowers individuals and institutions with limited resources to conduct biological experiments.