Formation of polyhydroxyalkanoates using agro and industrial waste as a substrate - a review

In the present scenario, rising environmental concerns of non-biodegradable plastic pollution and depletion of petroleum based raw materials lead to the development of biopolymers. The biodegradability of biopolymers gives them a specific advantage for the environmental concerns. Polyhydroxyalkanoates (PHAs) are a type of biopolymers which are synthesized by microorganisms. Although there are different substrates available in pure forms which are currently used in the production of PHA, 40% of production cost depends on the expensive substrate which is a major disadvantage and make it far from many applications. The use of an inexpensive carbon source which is high in organic matter content such as waste streams of process industries can make this process viable and diminish PHA production cost. This study explores the current research initiatives on various agricultural and industrial waste feedstocks, formulations and processing conditions for producing PHA in a way that is both inexpensive and beneficial to the environment. The creation of fermentation conditions and metabolic engineering techniques for promoting microbial growth and PHA synthesis were also discussed in the review.