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Platelet count and breast cancer stage
Andi Fahdrin1, Elridho Sampepajung2, John Pieter2
1Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Breast Disease
|January 15, 2023
Summary
This study found no significant link between platelet count and breast cancer stage. Further research is needed to understand thrombocytosis in cancer patients.
Area of Science:
- Oncology
- Hematology
Background:
- Thrombocytosis, or elevated platelet count, is observed in 10-57% of cancer patients.
- Tumor-secreted factors may cause thrombocytosis, a known poor prognostic indicator in malignancies.
- The correlation between platelet count and breast cancer stage requires further investigation.
Purpose of the Study:
- To investigate the relationship between platelet count and breast cancer stage.
- To analyze platelet counts in relation to tumor, node, metastasis (TNM) classification.
Main Methods:
- A cross-sectional study of 171 breast cancer patients was conducted from February 2020 to January 2021.
- Patient data were retrospectively collected from medical records.
- Staging utilized the American Joint Committee on Cancer (AJCC) 8th Edition TNM classification.
Main Results:
- Metastasis was present in 2.92% of patients and absent in 97.8%.
- No statistically significant differences in platelet counts were observed across the three breast cancer staging groups (p=0.952).
Conclusions:
- This study found no statistically significant relationship between increased platelet count and breast cancer staging using TNM classification.
- The role of thrombocytosis in breast cancer progression warrants additional research.
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