Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: The Efficacy of Oral Vitamin Supplementation in Dry Eye Disease: A Systematic Review.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026

Same author

The Efficacy of Oral Vitamin Supplementation in Dry Eye Disease: A Systematic Review.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026

Same author

Dose-dependent neurotoxic chemotherapy and corneal nerve morphological changes.

Clinical & experimental optometry·2026

Same author

The impact of probiotics and prebiotics on ocular and systemic inflammation in dry eye disease: a double-masked, randomised controlled trial.

Clinical & experimental optometry·2025

Same author

Evidence on the Use of Topical Ciclosporin for Ocular Surface Disease: A Systematic Review and Meta-Analysis-Response.

Clinical & experimental ophthalmology·2025

Same author

Evidence on the Use of Topical Ciclosporin for Ocular Surface Disease: A Systematic Review and Meta-Analysis.

Clinical & experimental ophthalmology·2025

Search research articles

Related Experiment Video

Updated: Aug 14, 2025

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

Conjunctival microcirculation in ocular and systemic microvascular disease.

Kofi Asiedu¹, Arun V Krishnan^2,3, Natalie Kwai⁴

¹School of Optometry and Vision Science, University of New South Wales, Sydney, Australia.

Clinical & Experimental Optometry

|January 15, 2023

Summary

The conjunctival microcirculation, a network of tiny blood vessels, can be measured using various techniques. Its study offers insights into ocular and systemic diseases like diabetes and Alzheimer's.

Keywords:

Conjunctiva diabetes hemodynamics microcirculation microvasculopathy

More Related Videos

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Related Experiment Videos

Last Updated: Aug 14, 2025

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Area of Science:

Ophthalmology
Microcirculation Research
Vascular Biology

Background:

The conjunctival microcirculation is an accessible microvascular network.
Quantitative assessment of conjunctival haemodynamics provides insights into ocular and systemic health.
Current measurement algorithms are manual or semi-automated.

Purpose of the Study:

To review conjunctival microcirculation characteristics and measurement techniques.
To explore the association between conjunctival microcirculation and disease-related microvascular abnormalities.

Main Methods:

Review of existing literature on conjunctival microcirculation.
Description of measurement techniques including functional slit-lamp biomicroscopy, laser doppler flowmetry, optical coherence tomography angiography, orthogonal polarized spectral imaging, computer-assisted intravitral microscopy, diffuse reflectance spectroscopy, and corneal confocal microscopy.

Main Results:

Conjunctival microcirculatory haemodynamics are linked to various diseases.
Established relationship between conjunctival microvascular function and conditions such as dry eye, Alzheimer's disease, diabetes, hypertension, sepsis, coronary microvascular disease, and sickle cell anaemia.

Conclusions:

Conjunctival microcirculation assessment is valuable for understanding microvascular haemodynamics.
This review highlights the diagnostic potential of conjunctival microcirculation in systemic and ocular diseases.