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Awareness on D-dimer assay among dental students
Shamaa Anjum1, Nabeel Ahmed1, Dhanraj M Ganapathy1
1Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Journal of Advanced Pharmaceutical Technology & Research
|January 16, 2023
Summary
Awareness of the D-dimer assay is low among dental practitioners, with over half unaware of its function. Enhanced education is recommended to improve understanding of this blood clot diagnostic tool.
Area of Science:
- Biochemistry
- Hematology
- Dental Medicine
Background:
- D-dimer molecules result from fibrinolysis, a process involving activated factor XIII (factor XIIIa), plasmin, and thrombin.
- Understanding diagnostic markers like D-dimer is crucial in clinical practice.
Purpose of the Study:
- To evaluate the awareness and knowledge of D-dimer assay among dental students.
- To identify gaps in understanding regarding the D-dimer assay's role and formation.
Main Methods:
- A cross-sectional study involving 100 dental practitioners.
- An online survey with 10 semiclosed, prevalidated questionnaires assessing knowledge, attitude, and practice.
- Descriptive and inferential statistical analysis of survey responses.
Main Results:
- 55% of participants lacked knowledge of what a D-dimer assay is.
- 46% correctly identified its use in ruling out blood clots.
- 54% understood that fibrin D-dimers form during fibrin strand creation.
- Knowledge was higher among CRRI participants compared to junior dental students.
Conclusions:
- Significant gaps exist in dental students' awareness of the D-dimer assay.
- Targeted educational programs are necessary to improve knowledge regarding D-dimer assays and their clinical relevance in dentistry.

