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Updated: Aug 14, 2025
Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Pulmonary aspergilloma management: 5 years of experience from a tertiary hospital
Hakan Keskin1, Hülya Dirol2, Nurgül Bozkurt2
1Department of Thoracic Surgery, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Introduction:
Pulmonary aspergilloma (PA) is a chronic lung infection. Lobectomy is the recommended surgical modality. However, recent studies have suggested that wedge resection may be better than lobectomy.
Aim:
We compared short-term complications and mortality according to surgical methods in pulmonary aspergilloma.
Material And Methods:
In this study, we analyzed the patients diagnosed with PA in the period 2015-2019 at a tertiary hospital. We obtained the data about the age, gender, smoking history, symptoms, radiological findings, operation technique, complications, length of hospital stay, and mortality from the electronic patient files. Then we compared short-term complications and mortality according to surgical methods in PA.
Results:
Of a total of 27 PA patients, 22 (81.5%) were male, with a mean age of 48.1 ±15.6 years. The most common symptom was dyspnea (48.1%). Nineteen (70.0%) of the patients had wedge resection and 6 (22.3%) of the patients had a lobectomy. Prolonged air leak and empyema were the most common postoperative complications. Prolonged air leak was significantly more common in lobectomy than in wedge resection (p = 0.046). There was no significant difference in other complications, hospital stay length, intensive care unit stay length or mortality between lobectomy and wedge resection.
Conclusions:
Wedge resection can be safely performed in aspergilloma. Prolonged air leak was less common in wedge resection than in lobectomy.
Insights
Wedge resection is a safe surgical option for pulmonary aspergilloma (PA), a chronic lung infection. This method showed fewer prolonged air leaks compared to lobectomy, with similar short-term outcomes.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Infectious Diseases
Background:
- Pulmonary aspergilloma (PA) is a chronic fungal lung infection.
- Lobectomy is traditionally recommended, but wedge resection is emerging as a potential alternative.
Purpose of the Study:
- To compare short-term complications and mortality between wedge resection and lobectomy for pulmonary aspergilloma.
Main Methods:
- Retrospective analysis of 27 PA patients treated between 2015-2019.
- Data collected included demographics, symptoms, radiological findings, surgical technique, complications, and outcomes.
- Comparison of short-term complications and mortality based on surgical method (wedge resection vs. lobectomy).
Main Results:
- Wedge resection was performed in 70% of patients, lobectomy in 22.3%.
- Prolonged air leak was significantly more frequent after lobectomy (p=0.046).
- No significant differences were observed in other complications, hospital stay, or mortality.
Conclusions:
- Wedge resection is a safe and effective surgical approach for pulmonary aspergilloma.
- It is associated with a lower incidence of prolonged air leak compared to lobectomy.
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